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White papers and issue briefs speak to national issues and their impact. We feature expert thought leaders who speak to the latest best practices and trends.

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September 2019 | Issue Brief

Pharmacogenomics: Improving outcomes, lowering costs by making precision medicine personal

Pharmacogenomics considers the role of the genome in drug response. It combines pharmacology and genomics, considering how the genetic makeup of an individual affects his/her response to drugs.

Today, more than ever before, we have the ability to target the right drug to improve a patient’s quality of life while also eliminating waste from non-optimized medications. This issue brief provides an overview of pharmacogenomics and showcases an employer case example of the opportunities and savings available to employers and health plans through integration of personalized medicine into benefit plan design.

Featuring the voices of Jane Cheshire Gilbert, CPA, director of retiree health care for the Teachers’ Retirement System of the State of Kentucky and Steve Goldberg, MD, vice president, medical affairs, population health and chief health officer, health & wellness, Quest Diagnostics, GTMRx Institute board member.

July 2019 | Issue Brief

CMM Practice in Real Life: Clinical Pharmacy Specialists on the VA Care Team

Comprehensive medication management is a team sport, with the potential to improve patient care and access while optimizing the skills of all clinicians on the team. The Veterans Health Administration has systematically integrated clinical pharmacy specialists into the care team to accomplish CMM for a range of chronic conditions. This issue brief and webinar explore the practice model and outcomes of CMM integration, as well as the tools that support the team. The lessons learned can be applied across a range of health care organizations—not just the VA or integrated delivery systems.

Featuring the voices of Anthony P. Morreale, Pharm.D., MBA, BCPS, FASHP, associate chief consultant for clinical pharmacy and policy for the Department of Veterans Affairs Pharmacy Benefits Management in VA Central Office; Julie Groppi, Pharm.D., FASHP, national PBM program manager for clinical pharmacy practice policy and standards for VA Central Office; and Brig. Gen. Allison Hickey (Ret.) USAF, former undersecretary of the Veterans Benefits Administration, CEO and founder of All In Solutions LLC and GTMRx Institute founding board member.
Hirsh McInnis GTMR Issue Brief 062019

June 2019 | Issue Brief

Training to advance Comprehensive Medication Management in practice: Acting on the $528B opportunity

What will it take to expand the use of comprehensive medication management? Greater awareness among payers, providers and patients is required, of course. More specifically, it will require education and training. Perhaps the most important aspect is integration of CMM—and the clinical pharmacist—into the care team. That takes savvy in team-based care integration, creating collaborative practice agreements and more. This issue brief explores the need for CMM and implications for pharmacy education and training, as well as how CMM is integrated into team-based care models.

Featuring the voices of Terry McInnis, MD, MPH, president and co-founder, Get the Medications Right Institute and Foundation; president, founder, Blue Thorn Inc.; and Jan Hirsch, BS Pharm, Ph.D.,  director and founding dean,  Pharmaceutical Sciences University of California, Irvine.

June 2019 Watanabe issue brief cover

June 2019 | Issue Brief

275,000 lives lost and a $528 billion price tag

Avoidable illness and death resulting from non-optimized medication therapy cost $528.4 billion in 2016, according to a peer-reviewed paper in the Annals of Pharmacotherapy. That represents 16% of the annual $3.2 trillion the U.S. spends on health care. This issue brief from Health2 Resources explores the research behind the figures and discusses the promise of comprehensive medication management as a systematic approach that can assure medications are appropriately and effectively used–making them both cost effective and assuring that all conditions are effectively managed with fewer side effects.

Featuring the voices of Terry McInnis, MD, MPH, president and co-founder, Get the Medications Right Institute and Foundation; president, founder, Blue Thorn Inc.; and Jonathan H. Watanabe, Pharm.D., M.S., Ph.D. BCGP, associate professor of clinical pharmacy, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego.

July 2018 | White Paper

The Patient Care Process for Delivering Comprehensive Medication Management (CMM)

Defining an intervention and ensuring consistency in delivery is necessary to establish a common understanding and set of expectations across key stakeholder groups including patients, pharmacists, physicians, other health care providers, and payers. This also allows the service to be recognized as distinct, yet complementary to care provided by the primary or specialty care provider. An intervention, such as comprehensive medication management (CMM), focused on optimizing medication use must be defined with a degree of specificity that allows consistent training of clinical pharmacists and other health care providers, replication of the service, and observable fidelity of the service across practitioners.

This white paper provides a framework and common language for understanding CMM and delivering it through a detailed patient care process. It was funded by the American College of Clinical Pharmacy, the American College of Clinical Pharmacy Research Institute and the UNC Eshelman Institute for Innovation. Content was developed by researchers at the UNC Eschelman School of Pharmacy, University of Minnesota College of Pharmacy and the University of Colorado.

Cover page Cost of Prescription Drug-related Morbidity and Mortality

March 2018 | Academic Research Article

Cost of Prescription Drug-Related Morbidity and Mortality

Public attention and recent policy activity has intensified focus on escalating medication prices. However, the actual cost of medication use extends beyond the up-front cost of purchasing medicines. It also encompasses the additional medical costs of morbidity and mortality resulting from nonoptimized medication regimens, including medication nonadherence. In this study, researchers Jonathan Watanabe, Pharm.D., M.S., Ph.D. BCGP,  Terry McInnis, MD, MPH and Jan Hirsch, BS Pharm, Ph.D. applied the most current nationally representative data sources to estimate the cost of prescription drug–related morbidity and mortality in the United States.

Findings: The estimated annual cost of prescription drug–related morbidity and mortality resulting from nonoptimized medication therapy was $528.4 billion in 2016 US dollars, with a plausible range of $495.3 billion to $672.7 billion.  The authors conclude that the estimated annual cost of drug-related morbidity and mortality resulting from nonoptimized medication therapy was $528.4 billion, equivalent to 16% of total US health care expenditures in 2016. Further, the authors propose expansion of comprehensive medication management programs by clinical pharmacists in collaborative practices with physicians and other prescribers as an effective and scalable approach to mitigate these avoidable costs and improve patient outcomes.
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May 2016 | Issue Brief

Get the medications right™: a dozen lessons

An issue brief from Health2 Resources, Get the medications right™: a dozen lessons, explores how comprehensive medication management is transforming care delivery for patients, pharmacists and other clinicians.

It identifies key lessons from the new report, Get the medications right™: a nationwide snapshot of expert practices–Comprehensive medication management in ambulatory/community pharmacy. The report, from Health2 Resources and Blue Thorn Inc. and sponsored by the Community Pharmacy Foundation, offers insight into how pharmacists, as both medication experts and clinicians, are optimizing medication use and making an impact on the practices and communities they serve.

The brief focuses on two CMM programs featured in the report: 
  • HealthPartners began paying for CMM-level services in 2006. Nearly everyone with a HealthPartners pharmacy benefit is eligible for CMM; that’s about 850,000 people. HealthPartners also employs pharmacists at 15 of its own clinics. Dan Rehrauer, PharmD, is the senior manager of the medication therapy management program.
  • Goodrich Pharmacy has 18 pharmacists at seven sites; five sites provide CMM. In 2015, they saw roughly 900 CMM patients and 700 disease-state medication management patients. Goodrich also contracts with six primary care clinics, providing CMM patient consultations for a flat fee. Steve Simenson, BPharm, FAPhA, DPNAP, is president and managing partner.
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June 2016 | Primary Care Learning Network White Paper

Get the medications right™: Comprehensive medication management and the role of the pharmacist in patient care. 

It’s long past the time to talk about “pilots” or “emerging practices” when discussing comprehensive medication management (CMM). CMM programs have been tested and retested, the results studied and documented. It’s not emerging: It has emerged—as a practice to improve outcomes, control costs and enhance the satisfaction of clinicians and patients alike. Health systems, patients, physicians—even payers—are beginning to understand the value of advanced clinical pharmacy services and the importance of integrating those services collaboratively into community/ambulatory team-based care, explains Terry McInnis, MD, MPH, CPE, FACOEM, in this white paper.

Do you agree? Join us. Together we can transform practice, use evidence wisely and implement real policy solutions.

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